mindromp

Adenosine 11th January 2012, 09:12 AM Every question that gets answered throws up two more. Take cell biology for example. There are thousands of proteins involved in cellular processes but for many of them all we have is a name. We don't know what they interact with, we don't know what they do exactly. Case in point. Fibroblast growth factor receptor 2 (FGFR2) is a transmembrane receptor found in epithelial tissue. In endometrial tissue, when stimulated by ligand it signals through two different paths and induces mitosis, or cell division. Once stimulated though, the receptor needs to be taken out of circulation, literally. Depending on the ligand it either gets endocytosed and degraded by lysosomes or gets endocytosed and then recycled back to the cell membrane. This has been known for a while and has pretty much entered into dogma. However, the receptor has been seen in the nucleus, specifically in or on nucleoli. The nucleolus is the site of ribosomal assembly, ...

Adenosine 11th January 2012, 09:12 AM Every question that gets answered throws up two more. Take cell biology for example. There are thousands of proteins involved in cellular processes but for many of them all we have is a name. We don't know what they interact with, we don't know what they do exactly. Case in point. Fibroblast growth factor receptor 2 (FGFR2) is a transmembrane receptor found in epithelial tissue. In endometrial tissue, when stimulated by ligand it signals through two different paths and induces mitosis, or cell division. Once stimulated though, the receptor needs to be taken out of circulation, literally. Depending on the ligand it either gets endocytosed and degraded by lysosomes or gets endocytosed and then recycled back to the cell membrane. This has been known for a while and has pretty much entered into dogma. However, the receptor has been seen in the nucleus, specifically in or on nucleoli. The nucleolus is the site of ribosomal assembly, ...

Adenosine 11th January 2012, 09:12 AM Every question that gets answered throws up two more. Take cell biology for example. There are thousands of proteins involved in cellular processes but for many of them all we have is a name. We don't know what they interact with, we don't know what they do exactly. Case in point. Fibroblast growth factor receptor 2 (FGFR2) is a transmembrane receptor found in epithelial tissue. In endometrial tissue, when stimulated by ligand it signals through two different paths and induces mitosis, or cell division. Once stimulated though, the receptor needs to be taken out of circulation, literally. Depending on the ligand it either gets endocytosed and degraded by lysosomes or gets endocytosed and then recycled back to the cell membrane. This has been known for a while and has pretty much entered into dogma. However, the receptor has been seen in the nucleus, specifically in or on nucleoli. The nucleolus is the site of ribosomal assembly, ...

Adenosine 11th January 2012, 09:12 AM Every question that gets answered throws up two more. Take cell biology for example. There are thousands of proteins involved in cellular processes but for many of them all we have is a name. We don't know what they interact with, we don't know what they do exactly. Case in point. Fibroblast growth factor receptor 2 (FGFR2) is a transmembrane receptor found in epithelial tissue. In endometrial tissue, when stimulated by ligand it signals through two different paths and induces mitosis, or cell division. Once stimulated though, the receptor needs to be taken out of circulation, literally. Depending on the ligand it either gets endocytosed and degraded by lysosomes or gets endocytosed and then recycled back to the cell membrane. This has been known for a while and has pretty much entered into dogma. However, the receptor has been seen in the nucleus, specifically in or on nucleoli. The nucleolus is the site of ribosomal assembly, ...

Adenosine 11th January 2012, 09:12 AM Every question that gets answered throws up two more. Take cell biology for example. There are thousands of proteins involved in cellular processes but for many of them all we have is a name. We don't know what they interact with, we don't know what they do exactly. Case in point. Fibroblast growth factor receptor 2 (FGFR2) is a transmembrane receptor found in epithelial tissue. In endometrial tissue, when stimulated by ligand it signals through two different paths and induces mitosis, or cell division. Once stimulated though, the receptor needs to be taken out of circulation, literally. Depending on the ligand it either gets endocytosed and degraded by lysosomes or gets endocytosed and then recycled back to the cell membrane. This has been known for a while and has pretty much entered into dogma. However, the receptor has been seen in the nucleus, specifically in or on nucleoli. The nucleolus is the site of ribosomal assembly, ...

Adenosine 11th January 2012, 09:12 AM Every question that gets answered throws up two more. Take cell biology for example. There are thousands of proteins involved in cellular processes but for many of them all we have is a name. We don't know what they interact with, we don't know what they do exactly. Case in point. Fibroblast growth factor receptor 2 (FGFR2) is a transmembrane receptor found in epithelial tissue. In endometrial tissue, when stimulated by ligand it signals through two different paths and induces mitosis, or cell division. Once stimulated though, the receptor needs to be taken out of circulation, literally. Depending on the ligand it either gets endocytosed and degraded by lysosomes or gets endocytosed and then recycled back to the cell membrane. This has been known for a while and has pretty much entered into dogma. However, the receptor has been seen in the nucleus, specifically in or on nucleoli. The nucleolus is the site of ribosomal assembly, ...

Adenosine 11th January 2012, 09:12 AM Every question that gets answered throws up two more. Take cell biology for example. There are thousands of proteins involved in cellular processes but for many of them all we have is a name. We don't know what they interact with, we don't know what they do exactly. Case in point. Fibroblast growth factor receptor 2 (FGFR2) is a transmembrane receptor found in epithelial tissue. In endometrial tissue, when stimulated by ligand it signals through two different paths and induces mitosis, or cell division. Once stimulated though, the receptor needs to be taken out of circulation, literally. Depending on the ligand it either gets endocytosed and degraded by lysosomes or gets endocytosed and then recycled back to the cell membrane. This has been known for a while and has pretty much entered into dogma. However, the receptor has been seen in the nucleus, specifically in or on nucleoli. The nucleolus is the site of ribosomal assembly, ...